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English: [Part of a] six-step sequence of the death of a cancer cell. A cancer cell has migrated through the holes of a matrix coated membrane from the top to the bottom, simulating natural migration of a invading cancer cell between, and sometimes through, the vascular endothelium. Notice the spikes or pseudopodia that are characteristic of an invading cancer cell (1). A buffy coat containing red blood cells, lymphocytes and macrophages is added to the bottom of the membrane. A group of macrophages identify the cancer cell as foreign matter and start to stick to the cancer cell, which still has its spikes (2). Shown: Macrophages begin to fuse with, and inject its toxins into, the cancer cell. The cell starts rounding up and loses its spikes (3). As the macrophage cell becomes smooth (4). The cancer cell appears lumpy in the last stage before it dies. These lumps are actually the macrophages fused within the cancer cell (5). The cancer cell then loses its morphology, shrinks up and dies (6). Photo magnification: 3: x8,000 Type: B & W print
العربية : سلسلة من ست خطوات لموت خلية سرطانية. هاجرت خلية سرطانية عبر فتحات من الغشاء المكسو بالمطرس من الأعلى إلى الأسفل محاكية الهجرة الطبيعية للخلية السرطانية الغازية بين -وأحيانا عبر- البطانة الوعائية. لاحظ الشوكات أو الأقدام الكاذبة المميِّزة للخلية السرطانية الغازية (1). يُضاف كساء (طبقة) تحتوي على خلايا الدم الحمراء واللمفاويات والبالعات الكبيرة إلى أسفل الغشاء. تتعرف البالعات الكبيرة على الخلية السرطانية على أنها مادة دخيلة وتبدأ بالالتصاق بها وهي مازالت تملك شوكاتها (2). ظاهر في الصورة: تبدأ البالعات الكبيرة في الاندماج وحقن السموم داخل الخلية السرطانية. تبدأ الخلية السرطانية في اتخاذ شكل دائري وتفقد شوكاتها (3). بينما تصبح البالعة الكبيرة ملساء (4). تظهر الخلايا السرطانية متكتلة ومتنتئة في المرحلة الأخيرة قبل موتها. الكتل والنتوءات هي بالعات كبيرة مندمجة داخل الخلية السرطانية (5). تفقد الخلية السرطانية شكلها بعد ذلك وتتقلص ثم تموت (6). تكبير الصورة: 3: x8,000، ونوعها: نسخة بالأبيض والأسود.
Sanasi Date Created: October 1988
Manba Image and description: Dr. Raowf Guirguis. National Cancer Institute
Muallif Susan Arnold (photographer)
Ruxsat
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Public domain
This work is in the public domain in the United States because it is a work prepared by an officer or employee of the United States Government as part of that person’s official duties under the terms of Title 17, Chapter 1, Section 105 of the US Code. Note: This only applies to original works of the Federal Government and not to the work of any individual U.S. state, territory, commonwealth, county, municipality, or any other subdivision. This template also does not apply to postage stamp designs published by the United States Postal Service since 1978. (See § 313.6(C)(1) of Compendium of U.S. Copyright Office Practices). It also does not apply to certain US coins; see The US Mint Terms of Use.
This file has been identified as being free of known restrictions under copyright law, including all related and neighboring rights.
http://visualsonline.cancer.gov/about.cfm "All images are in the public domain and may be used, linked, or reproduced without permission. If an image is used, credit should be given to the listed source and/or author."

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03:15, 2006-yil 4-oktyabr03:15, 2006-yil 4-oktyabr dagi versiya uchun tasvir2 289 × 1 800 (1,02 MB)DO11.10{{Information |Description=[Part of a] six-step sequence of the death of a cancer cell. A cancer cell has migrated through the holes of a matrix coated membrane from the top to the bottom, simulating natural migration of a invading cancer cell between, an

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