2-degidro-3-deoksi-D-glyukonat 6-degidrogenaza

Enzimologiyada 2-dehidro-3-deoksi-D-glyukonat 6-dehidrogenaza (EC)) kimyoviy reaksiyani katalizlovchi ferment hisoblanadi.

2-dehidro-3-deoksi-D-glyukonat + NADP ⁺ $\rightleftharpoons$ (4S,5S)-4,5-dihidroksi-2,6-dioksoheksanoat + NADPH + H ⁺

Shunday qilib, bu fermentning ikkita substrati 2-dehidro-3-deoksi-D-glyukonat va NADP <sup id="mwFA">+</sup>, uning 3 ta oxirgi mahsuloti esa (4S, 5S) −4,5-dihidroksi-2,6-dioksoheksanoat, NADPH va H <sup id="mwGQ">+</sup>.

Bu ferment oksidoreduktazalar oilasiga, xususan donorning CH-OH guruhiga NAD ⁺ yoki NADP ⁺ akseptor sifatida taʼsir etuvchi fermentlarga tegishli. Ushbu ferment sinfining sistematik nomi 2-degidro-3-deoksi-D-glyukonat: NADP ⁺ 6-oksidoreduktoza. Umumiy ishlatiladigan boshqa nomlar orasida 2-keto-3-deoksi-D-glyukonat dehidrogenaza va 2-keto-3-deoksiglyukonat dehidrogenaza kabilari mavjud.

Manbalar

• "Alginic acid metabolism in bacteria. II. The enzymatic reduction of 4-deoxy-L-erythro-5-hexoseulose uronic acid to 2-keto-3-deoxy-D-gluconic acid". The Journal of Biological Chemistry 237: 317–21. February 1962. PMID 14488585. https://archive.org/details/sim_journal-of-biological-chemistry_1962-02_237_2/page/317.