2-degidropantolakton reduktaza (A-maxsus)
Qiyofa
Enzimologiyada 2-degidropantolakton reduktaza (A-maxsus) (EC)) kimyoviy reaksiyani katalizlovchi ferment hisoblanadi.
- ®-pantolakton + NADP + 2-degidropantolakton + NADPH + H +
Shunday qilib, bu fermentning ikkita substrati ®-pantolakton va NADP <sup id="mwFA">+</sup>, uning 3 ta oxirgi mahsuloti esa 2-degidropantolakton, NADPH va H <sup id="mwGQ">+</sup> dir.
Bu ferment oksidoreduktazalar oilasiga, xususan oksidlovchining CH-OH guruhiga NAD + yoki NADP + akseptor sifatida taʼsir etuvchi fermentlarga tegishli. Ushbu ferment sinfining tizimli nomi ®-pantolakton: NADP + oksidoreduktaza (A-maxsus) . Umumiy foydalanishdagi boshqa nomlar orasida 2-oksopantoil lakton reduktaza, ketopantoil lakton reduktaza, 2-ketopantoil lakton reduktaza va 2-degidropantoil-lakton reduktaza (A-maxsus) kabilari mavjud.
Manbalar
[tahrir | manbasini tahrirlash]- "Ketopantoyl lactone and ketopantoic acid reductases: Characterization of the reactions and purification of two forms of ketopantoyl lactone reductase". J. Biol. Chem. 249 (15): 4689–4695. Aug 10, 1974. PMID 4603075. https://archive.org/details/sim_journal-of-biological-chemistry_1974-08-10_249_15/page/4689.
- "Ketopantoic acid and ketopantoyl lactone reductases: Stereospecificity of transfer of hydrogen from reduced nicotinamide adenine dinucleotide phosphate". J. Biol. Chem. 250 (6): 2311–2314. March 25, 1975. PMID 234966. https://archive.org/details/sim_journal-of-biological-chemistry_1975-03-25_250_6/page/2311.